Weis, Robert’s team published research in Tetrahedron in 59 | CAS: 6972-05-0

Tetrahedron published new progress about 6972-05-0. 6972-05-0 belongs to catalysis-chemistry, auxiliary class Thiourea,Amine,Aliphatic hydrocarbon chain,Amide, name is 1,1-Dimethylthiourea, and the molecular formula is C18H35NO, Application In Synthesis of 6972-05-0.

Weis, Robert published the artcileSynthesis of new analogs of diphenylpyraline, Application In Synthesis of 6972-05-0, the publication is Tetrahedron (2003), 59(9), 1403-1411, database is CAplus.

1-Unsubstituted 4-dimethylamino-5,6-dihydropyridine-2(1H)-thiones were converted to isomeric piperidin-4-ols which were separated and N-methylated to 2-substituted 1-methylpiperidin-4-ols. Their 1-Ph analogs were prepared from 4-dimethylamino-5,6-dihydro-1-phenylpyridine-2(1H)-thiones. After their conversion to dihydro-1-phenylpyridin-4(1H)-ones the hydrogenation gave isomeric 1-phenylpiperidin-4-ols, which were separated O-Alkylation of the 1-substituted piperidin-4-ols by various methods yielded 2-substituted analogs of diphenylpyraline. Their antimycobacterial activity was examined The configurations and conformations of the piperidine derivatives were investigated by NMR spectroscopy.

Tetrahedron published new progress about 6972-05-0. 6972-05-0 belongs to catalysis-chemistry, auxiliary class Thiourea,Amine,Aliphatic hydrocarbon chain,Amide, name is 1,1-Dimethylthiourea, and the molecular formula is C18H35NO, Application In Synthesis of 6972-05-0.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia