Weise, Christian F. published the artcileOrganocatalytic Access to Enantioenriched Dihydropyran Phosphonates via an Inverse-Electron-Demand Hetero-Diels-Alder Reaction, Recommanded Product: (E)-3-(3-Nitrophenyl)acrylic acid, the publication is Journal of Organic Chemistry (2014), 79(8), 3537-3546, database is CAplus and MEDLINE.
The enantioselective inverse-electron-demand hetero-Diels-Alder reaction of the remote olefin functionality in dienamines was developed by the simultaneous activation of ¦Á,¦Â-unsaturated aldehydes and acyl phosphonates. The dual activation is based on an organocatalyst that activates both the ¦Á,¦Â-unsaturated aldehyde, through dienamine formation, and the acyl phosphonate by H-bonding. The enantioselective reaction gave dihydropyran frameworks with three contiguous stereogenic centers. Different substitution patterns are possible for both the heterodiene and the dienophile, and the target products were obtained in good yields and up to 92% ee. The potential of the reaction is demonstrated by transformation of the products into valuable and complex synthons.
Journal of Organic Chemistry published new progress about 1772-76-5. 1772-76-5 belongs to catalysis-chemistry, auxiliary class Benzenes, name is (E)-3-(3-Nitrophenyl)acrylic acid, and the molecular formula is C10H14O, Recommanded Product: (E)-3-(3-Nitrophenyl)acrylic acid.
Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia