Jiang, Bing published the artcileSelective Oxidative Cleavage of the C-C Bond in ¦Á,¦Â-Epoxy Ketone into Carbonyl Compounds, Name: 2-Methylbenzoic acid, the publication is ACS Omega (2022), 7(25), 21608-21614, database is CAplus and MEDLINE.
This method afforded aromatic carbonyl compounds under TBHP via selective oxidative cleavage of the C-C bond in ¦Á,¦Â-epoxy ketones. Aromatic acid came from the aroyl section, and aromatic aldehyde came from the other aromatic group. TBHP acted as a free radical initiator and oxidant. The reaction within the solvent went through a ring-opening addition, cleavage of the C-C bond in the ethylene oxide section, and oxidation, affording the target compounds in moderate to good yields. The HPLC yield of aromatic aldehyde was up to 91%. The HPLC yield of aromatic acid was up to 99%. The reaction under solvent-free conditions gave two kinds of aromatic acids coming from different moieties of ¦Á,¦Â-epoxy ketone via the further oxidation of aromatic aldehyde. The substituent effect was discussed, and the reaction mechanism was proposed. This method allowed the reaction to occur in a simple system metal-free.
ACS Omega published new progress about 118-90-1. 118-90-1 belongs to catalysis-chemistry, auxiliary class Carboxylic acid,Benzene,Natural product, name is 2-Methylbenzoic acid, and the molecular formula is C8H8O2, Name: 2-Methylbenzoic acid.
Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia