Lee, David Y. W.’s team published research in Bioorganic & Medicinal Chemistry Letters in 27 | CAS: 4230-93-7

Bioorganic & Medicinal Chemistry Letters published new progress about 4230-93-7. 4230-93-7 belongs to catalysis-chemistry, auxiliary class Alkenyl,Nitro Compound,Benzene,Ether, name is 1,2-Dimethoxy-4-(2-nitrovinyl)benzene, and the molecular formula is C10H11NO4, Recommanded Product: 1,2-Dimethoxy-4-(2-nitrovinyl)benzene.

Lee, David Y. W. published the artcileAsymmetric total synthesis of tetrahydroprotoberberine derivatives and evaluation of their binding affinities at dopamine receptors, Recommanded Product: 1,2-Dimethoxy-4-(2-nitrovinyl)benzene, the publication is Bioorganic & Medicinal Chemistry Letters (2017), 27(6), 1437-1440, database is CAplus and MEDLINE.

Cocaine addiction remains a serious challenge for clin. and medical research because there is no effective pharmacol. treatment. L-THP I, a natural product isolated from Corydalis yanhusuo W. T. Wang, is one of the most frequently used traditional herbs to treat drug addiction in China. Our laboratory first reported that its demethylated metabolites had high affinity at dopamine D1, D2, and D5 receptors. Here we report the chem. synthesis of these metabolites and other derivatives and their binding affinities at dopamine receptors. The synthesis of these bioactive metabolites will allow further in vivo study of their potential in treating cocaine addiction.

Bioorganic & Medicinal Chemistry Letters published new progress about 4230-93-7. 4230-93-7 belongs to catalysis-chemistry, auxiliary class Alkenyl,Nitro Compound,Benzene,Ether, name is 1,2-Dimethoxy-4-(2-nitrovinyl)benzene, and the molecular formula is C10H11NO4, Recommanded Product: 1,2-Dimethoxy-4-(2-nitrovinyl)benzene.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia