Shen, Zhenpeng published the artcileIron-Promoted Decarboxylation of Arylacetic Acids for the Synthesis of Aromatic Nitriles with Sodium Nitrite as the Nitrogen Source, Quality Control of 104-03-0, the publication is Synlett (2020), 31(18), 1805-1808, database is CAplus.
A new and effective method was developed for the synthesis of aromatic nitriles ArCN (Ar = 4-chlorophenyl, naphthalen-1-yl, thiophen-2-yl, etc.) (I) from arylacetic acids ArCH2C(O)OH (II) by using NaNO2 as the nitrogen source and Fe(OTf)3 as the promoter at 50¡ãC. A series of arylacetic acids II underwent this transformation to give the targeted products I in yields of 51-90%. Because of the mild conditions, the reaction is compatible with a broad range of functional groups, including ester, carboxy, hydroxy, acetamido, halo, nitro, cyano, methoxy, and even highly reactive formyl groups.
Synlett published new progress about 104-03-0. 104-03-0 belongs to catalysis-chemistry, auxiliary class Nitro Compound,Carboxylic acid,Benzene, name is 4-Nitrophenylacetic acid, and the molecular formula is C18H21BO4, Quality Control of 104-03-0.
Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia