Lopez-Garcia, M. Angeles published the artcile1-alkoxyamino-2-nitroalkanes as key building blocks for a chemo- and diastereoselective synthesis of a new type of polyfunctionalized N-alkoxypiperidine, Application of 1,2-Dimethoxy-4-(2-nitrovinyl)benzene, the publication is European Journal of Organic Chemistry (2010), 5482-5488, S5482/1-S5482/13, database is CAplus.
A highly efficient conversion of ¦Â-nitrostyrenes into a new kind of functionalized N-alkoxy-2-hydroxypiperidine, e.g. I, in two steps was developed, giving excellent yields and diastereoselectivity. The prepared compounds are the first examples of N-alkoxy-2-hydroxypiperidines. The synthetic approach involved the conjugate addition of alkoxyamines to ¦Â-nitrostyrenes, followed by Michael addition of the isolated nitro-alkoxyamines to ¦Á,¦Â-unsaturated carbonyl compounds, and intramol. addition of the alkoxyamino group to the carbonyl functionality of the (non-isolated) adducts. Although three stereogenic centers are formed, only one diastereoisomer was detected. This unprecedented sequence of reactions can also be performed in a one-pot fashion.
European Journal of Organic Chemistry published new progress about 4230-93-7. 4230-93-7 belongs to catalysis-chemistry, auxiliary class Alkenyl,Nitro Compound,Benzene,Ether, name is 1,2-Dimethoxy-4-(2-nitrovinyl)benzene, and the molecular formula is C10H11NO4, Application of 1,2-Dimethoxy-4-(2-nitrovinyl)benzene.
Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia