Spears, Richard J. published the artcileA novel thiol-labile cysteine protecting group for peptide synthesis based on a pyridazinedione (PD) scaffold, HPLC of Formula: 71989-31-6, the publication is Chemical Communications (Cambridge, United Kingdom) (2022), 58(5), 645-648, database is CAplus and MEDLINE.
Herein we report a thiol-labile cysteine protecting group based on an unsaturated pyridazinedione (PD) scaffold. We establish compatibility of the PD in conventional solid phase peptide synthesis (SPPS), showcasing this in the on-resin synthesis of biol. relevant oxytocin. Furthermore, we establish the applicability of the PD protecting group towards both microwave-assisted SPPS and native chem. ligation (NCL) in a model system.
Chemical Communications (Cambridge, United Kingdom) published new progress about 71989-31-6. 71989-31-6 belongs to catalysis-chemistry, auxiliary class Amino acide derivatives,pyrrolidine, name is Fmoc-Pro-OH, and the molecular formula is C11H21BF4N2O2, HPLC of Formula: 71989-31-6.
Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia