Kameo, Kazuya’s team published research in Chemical & Pharmaceutical Bulletin in 36 | CAS: 15732-75-9

Chemical & Pharmaceutical Bulletin published new progress about 15732-75-9. 15732-75-9 belongs to catalysis-chemistry, auxiliary class Alkenyl,Carboxylic acid,Benzene,Ketone, name is 2-Methylene-4-oxo-4-phenylbutanoic acid, and the molecular formula is C11H10O3, Recommanded Product: 2-Methylene-4-oxo-4-phenylbutanoic acid.

Kameo, Kazuya published the artcileStudies on antirheumatic agents: 3-benzoylpropionic acid derivatives, Recommanded Product: 2-Methylene-4-oxo-4-phenylbutanoic acid, the publication is Chemical & Pharmaceutical Bulletin (1988), 36(6), 2050-60, database is CAplus and MEDLINE.

As part of the search for new antirheumatic agents, three types of 3-benzoylpropionic acid derivatives, e.g. RCOCH2CH(SR1)CO2R2, RCOCH2CH(CH2SR1)CO2R2, and RCOCH(CH2SR1)CH2CO2R2 (R = Ph, substituted phenyl; R1 = Ac, Et, EtCO, Bz; R2 = H, Et, Me, CH2Ph), having a mercapto moiety in their structures were prepared and tested for suppressing activity on adjuvant arthritis in Sprague-Dawley rats. A structure-activity relationship study showed that substitution on the Ph ring contributed to the activity and the most favorable substituent was different in each type of derivative

Chemical & Pharmaceutical Bulletin published new progress about 15732-75-9. 15732-75-9 belongs to catalysis-chemistry, auxiliary class Alkenyl,Carboxylic acid,Benzene,Ketone, name is 2-Methylene-4-oxo-4-phenylbutanoic acid, and the molecular formula is C11H10O3, Recommanded Product: 2-Methylene-4-oxo-4-phenylbutanoic acid.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia