Stejskalova, Anna published the artcileBiologically Inspired, Cell-Selective Release of Aptamer-Trapped Growth Factors by Traction Forces, Computed Properties of 1395786-30-7, the publication is Advanced Materials (Weinheim, Germany) (2019), 31(7), n/a, database is CAplus and MEDLINE.
Biomaterial scaffolds that are designed to incorporate dynamic, spatiotemporal information have the potential to interface with cells and tissues to direct behavior. Here, a bioinspired, programmable nanotechnol.-based platform is described that harnesses cellular traction forces to activate growth factors, eliminating the need for exogenous triggers (e.g., light), spatially diffuse triggers (e.g., enzymes, pH changes), or passive activation (e.g., hydrolysis). Flexible aptamer technol. is used to create modular, synthetic mimics of the Large Latent Complex that restrains transforming growth factor-¦Â1 (TGF-¦Â1). This flexible nanotechnol.-based approach is shown here to work with both platelet-derived growth factor-BB (PDGF-BB) and vascular endothelial growth factor (VEGF-165), integrate with glass coverslips, polyacrylamide gels, and collagen scaffolds, enable activation by various cells (e.g., primary human dermal fibroblasts, HMEC-1 endothelial cells), and unlock fundamentally new capabilities such as selective activation of growth factors by differing cell types (e.g., activation by smooth muscle cells but not fibroblasts) within clin. relevant collagen sponges.
Advanced Materials (Weinheim, Germany) published new progress about 1395786-30-7. 1395786-30-7 belongs to catalysis-chemistry, auxiliary class Inhibitor, name is Dbco-maleimide, and the molecular formula is 0, Computed Properties of 1395786-30-7.
Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia