Huang, Liangbin published the artcileReductive Decarboxylative Alkynylation of N-Hydroxyphthalimide Esters with Bromoalkynes, HPLC of Formula: 1949-41-3, the publication is Angewandte Chemie, International Edition (2017), 56(39), 11901-11905, database is CAplus and MEDLINE.
A new method for the synthesis of terminal and internal alkynes from the Ni-catalyzed decarboxylative coupling of N-hydroxyphthalimide esters and bromoalkynes is presented. This reductive cross-electrophile coupling is the 1st to use a C(sp)-X electrophile, and appears to proceed via an alkynylnickel intermediate. The internal alkyne products were obtained in yields of 41-95% without the need for a photocatalyst, light, or a strong oxidant. The reaction displays a broad scope of carboxylic acid and alkyne coupling partners, and can tolerate an array of functional groups, including carbamate NH, halogen, nitrile, olefin, ketone, and ester moieties. Mechanistic studies suggest that this process does not involve an alkynylmanganese reagent and instead proceeds through Ni-mediated bond formation.
Angewandte Chemie, International Edition published new progress about 1949-41-3. 1949-41-3 belongs to catalysis-chemistry, auxiliary class Carboxylic acid,Benzene, name is 2-Methyl-4-phenylbutanoic acid, and the molecular formula is C11H14O2, HPLC of Formula: 1949-41-3.
Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia