Webb, Eric W. published the artcileNucleophilic (Radio)Fluorination of Redox-Active Esters via Radical-Polar Crossover Enabled by Photoredox Catalysis, Name: 2-(4-(tert-Butyl)phenoxy)acetic acid, the publication is Journal of the American Chemical Society (2020), 142(20), 9493-9500, database is CAplus and MEDLINE.
A redox-neutral method for nucleophilic fluorination of N-hydroxyphthalimide esters e.g., I using an Ir photocatalyst under visible light irradiation was reported. The method provides access to a broad range of aliphatic fluorides, including primary, secondary, and tertiary benzylic fluorides as well as unactivated tertiary fluorides, that are typically inaccessible by nucleophilic fluorination due to competing elimination. In addition, the decarboxylative fluorination conditions are readily adapted to radiofluorination with [18F]KF. The reactions proceed by two electron transfers between the Ir catalyst and redox-active ester substrate to afford a carbocation intermediate that undergoes subsequent trapping by fluoride. Examples of trapping with O- and C-centered nucleophiles and deoxyfluorination via N-hydroxyphthalimidoyl oxalates are also presented, suggesting that this approach may offer a general blueprint for affecting redox-neutral SN1 substitutions under mild conditions.
Journal of the American Chemical Society published new progress about 1798-04-5. 1798-04-5 belongs to catalysis-chemistry, auxiliary class Carboxylic acid,Benzene,Ether, name is 2-(4-(tert-Butyl)phenoxy)acetic acid, and the molecular formula is C20H21ClN4O4, Name: 2-(4-(tert-Butyl)phenoxy)acetic acid.
Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia