Light, B. published the artcileEffect of triethylenetetramine dihydrochloride on the antibiotic susceptibility of Pseudomonas aeruginosa, Quality Control of 38260-01-4, the publication is Antimicrobial Agents and Chemotherapy (1978), 13(6), 979-84, database is CAplus and MEDLINE.
A chelating agent, triethylenetetramine-2HCl [38260-01-4], interacted synergistically in vitro with both gentamicin [1403-66-3] and carbenicillin [4697-36-3] against a clin. isolate of P. aeruginosa designated Ps 15. The minimal inhibitory concentrations of carbenicillin and gentamicin for Ps 15 in a 50% serum-Trypticase soy broth were 250 and 72.9 ¦Ìg/mL, resp. However, addition of triethylenetetramine-2HCl to the 50% serum-Trypticase soy broth decreased the minimal inhibitory concentrations of both antibiotics ?10-fold. A comparison of the growth of Ps 15 in 50% serum-Trypticase soy broth containing either of the antibiotics showed that a rapid decrease in the percentage of survivors only occurred when the chelating agent was present.
Antimicrobial Agents and Chemotherapy published new progress about 38260-01-4. 38260-01-4 belongs to catalysis-chemistry, auxiliary class Chelating Agents, name is N1,N1′-(Ethane-1,2-diyl)bis(ethane-1,2-diamine) dihydrochloride, and the molecular formula is C6H20Cl2N4, Quality Control of 38260-01-4.
Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia