Isiklan, Muhammet published the artcileSynthesis, structural characterization, and cytotoxic activity of new spirocyclic octachlorocyclotetraphosphazenes, Quality Control of 140-28-3, the publication is Phosphorus, Sulfur and Silicon and the Related Elements (2016), 191(9), 1216-1222, database is CAplus.
Octachlorocyclotetraphosphazene, N4P4Cl8, (1) was reacted with N,N’-dibenzylethylenediamine to synthesize partially substituted monospiro- (2), dispiro- (5) and tetraspirocyclotetraphosphazene (8) derivatives The reactions of and with excess pyrrolidine and morpholine produced fully substituted pyrrolidino (3 and 6) morpholino (4 and 7) spirocyclotetraphosphazenes. The structures of the compounds were determined with 1D (1H, 13C, 31P, and DEPT) NMR, 2D (HSQC) NMR, ESI-MS, FTIR, and elemental anal. The solid-state structures of and were examined by x-ray crystallog. In 7, intramol. C-H¡¤¡¤¡¤O hydrogen bonds link the mols. into centrosym. dimmers. The cytotoxic activity of all the compounds against human cervix carcinoma cell lines (HeLa) was investigated. The study showed that these compounds exert limited cytotoxic, apoptotic and necrotic effects on HeLa cancer cell lines.
Phosphorus, Sulfur and Silicon and the Related Elements published new progress about 140-28-3. 140-28-3 belongs to catalysis-chemistry, auxiliary class Benzenes, name is N1,N2-Dibenzylethane-1,2-diamine, and the molecular formula is C16H20N2, Quality Control of 140-28-3.
Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia