Bream, John B.’s team published research in Helvetica Chimica Acta in 60 | CAS: 6972-05-0

Helvetica Chimica Acta published new progress about 6972-05-0. 6972-05-0 belongs to catalysis-chemistry, auxiliary class Thiourea,Amine,Aliphatic hydrocarbon chain,Amide, name is 1,1-Dimethylthiourea, and the molecular formula is C3H8N2S, Application In Synthesis of 6972-05-0.

Bream, John B. published the artcileSeven-membered heterocycles. 25. Synthesis of 1- and 5-aryl-2,4-benzothiazepines, Application In Synthesis of 6972-05-0, the publication is Helvetica Chimica Acta (1977), 60(8), 2872-80, database is CAplus.

Benzothiazepines I (R = H, Me, R1 = H, 7-Cl, R2 = H) and II [R1 = R2 = H, R3 = R4 = Me, R3R4 = (CH2)2-4; R1 = 8-Cl, R2 = H, R3R4 = (CH2)3; R1 = H, R2 = Me, F, R3R4 = (CH2)3] were prepared by treating the xylyl dibromides III with thioureas and cyclizing with base. The intermediate IV gave V. Benzothiazepines VI (R5 = H, 7-Cl, 8-Cl; R6 = H, Me, CH2CH2Ph; R7 = H, Me) and VII [R5 = same; R8 = H, Me, R9 = Me; R8R9 = (CH2)2-3] were obtained by cyclizing VIII.

Helvetica Chimica Acta published new progress about 6972-05-0. 6972-05-0 belongs to catalysis-chemistry, auxiliary class Thiourea,Amine,Aliphatic hydrocarbon chain,Amide, name is 1,1-Dimethylthiourea, and the molecular formula is C3H8N2S, Application In Synthesis of 6972-05-0.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia