Fabre, C. published the artcileGem effects: basicity measurement. The doubtful nature of generalities of conformational effects of geminal disubstitution, Recommanded Product: Propane-1,3-diamine dihydrochloride, the publication is Nouveau Journal de Chimie (1980), 4(10), 609-14, database is CAplus.
Geminal disubstitution does not systematically involve a decrease in the distance between the ends of an aliphatic chain. Thus, the pK values of I (R = H, Me) are identical. On the other hand, basicity differences were observed for II (m = 1; R = H, Me); no basicity differences were observed for II (m = 2, 3; R = H, Me).
Nouveau Journal de Chimie published new progress about 10517-44-9. 10517-44-9 belongs to catalysis-chemistry, auxiliary class Salt,Amine,Aliphatic hydrocarbon chain, name is Propane-1,3-diamine dihydrochloride, and the molecular formula is C3H12Cl2N2, Recommanded Product: Propane-1,3-diamine dihydrochloride.
Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia