Zhao, Haoqiang published the artcileRh(I)-Catalyzed C6-Selective Decarbonylative Alkylation of 2-Pyridones with Alkyl Carboxylic Acids and Anhydrides, Application of 3-Benzoylpropionicacid, the publication is Organic Letters (2020), 22(11), 4228-4234, database is CAplus and MEDLINE.
A Rh-catalyzed chelation-assisted C6-selective C-H activation/alkylation of 2-pyridones e.g., 1-(pyridin-2-yl)-1,2-dihydropyridin-2-one with readily available anhydrides RC(O)OC(O)R (R = Me, Et, 2-methylpropyl, etc.) or alkyl carboxylic acids R1C(O)OH (R1 = nonyl, cyanoethyl, cyclohexyl, etc.) is introduced. The reaction proceeds via substrate decarbonylation. This approach merges C-H functionalization with readily available anhydrides, allowing for the efficient synthesis of various C6-alkylated 2-pyridones e.g., 6-methyl-2H-[1,2′-bipyridin]-2-one with good functional group tolerance.
Organic Letters published new progress about 2051-95-8. 2051-95-8 belongs to catalysis-chemistry, auxiliary class Carboxylic acid,Benzene,Ketone, name is 3-Benzoylpropionicacid, and the molecular formula is C14H26O2, Application of 3-Benzoylpropionicacid.
Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia