He, Qiyuan published the artcilePalladium-Catalyzed Site-Selective [5 + 1] Annulation of Aromatic Amides with Alkenes: Acceleration of ¦Â-Hydride Elimination by Maleic Anhydride from Palladacycle, Name: 2-Methylbenzoic acid, the publication is ACS Catalysis (2022), 12(2), 1595-1600, database is CAplus.
The palladium-catalyzed reaction of 2-methylbenzamides with acrylic esters, leading to the production of isoquinolinones, is reported. The reaction occurs exclusively at the ortho Me C-H bond via a six-membered palladacycle and not at the ortho C-H bond via a five-membered palladacycle. A key to the success of the reaction is the use of maleic anhydride as a ligand. Computational analyses suggest that the coordination of the maleic anhydride ligand highly stabilizes the transition state for ¦Â-hydride elimination and accelerates the ¦Â-hydride elimination.
ACS Catalysis published new progress about 118-90-1. 118-90-1 belongs to catalysis-chemistry, auxiliary class Carboxylic acid,Benzene,Natural product, name is 2-Methylbenzoic acid, and the molecular formula is C8H8O2, Name: 2-Methylbenzoic acid.
Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia