Tharamak, Sorachat published the artcileSynthesis of thymyl esters and their insecticidal activity against Spodoptera litura (Lepidoptera: Noctuidae), Related Products of catalysis-chemistry, the publication is Pest Management Science (2020), 76(3), 928-935, database is CAplus and MEDLINE.
Thymol, a natural phenolic monoterpene originating from Thymus vulgaris, is recognized as a safe and potent botanical insecticide to many insects. The structural modification of thymol into thymyl esters is a potential approach for the development of novel insecticides, which showed more toxicity than thymol. However, there are no reports on the insecticidal activity of thymyl esters to control Spodoptera litura. Thymol was structurally modified into ten thymyl esters by esterification using a new reagent, PPh3/Br3CSO2Ph. The insecticidal activity of these compounds was examined against the second instars of Spodoptera litura using a topical application. Among the ten thymyl esters evaluated, thymyl cinnamate was the most toxic with LD50 = 0.41 and 0.34 ¦Ìg/larva after 24 and 48 h posttreatment, resp. In addition, thymyl cinnamate-treated larvae showed increasing carboxylesterase and acetylcholinesterase activities in vivo experiment, whereas glutathione S-transferase activity showed no significant difference. Thymyl cinnamate were first reported to exhibit toxicity against S. litura 2.41-2.46 fold more efficient than thymol. However, the detailed biochem. interactions are necessary for further development of novel insecticides.
Pest Management Science published new progress about 104-03-0. 104-03-0 belongs to catalysis-chemistry, auxiliary class Nitro Compound,Carboxylic acid,Benzene, name is 4-Nitrophenylacetic acid, and the molecular formula is C9H8N2O3, Related Products of catalysis-chemistry.
Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia