Yuasa, M. published the artcileComputer-controlled synthesis of [18F]FDG by the tetrabutylammonium method: achievement of high yield, purity, reproducibility, reliability, and safety, HPLC of Formula: 17351-62-1, the publication is Applied Radiation and Isotopes (1997), 48(2), 201-205, database is CAplus.
The authors constructed a computer-controlled apparatus of no-carrier-added [18F]fluorodeoxyglucose ([18F]FDG) synthesis for routine clin. use. High yield, high reproducibility, and high quality of the product were achieved. The main step of the reaction is nucleophilic fluorination of the synthetic precursor, acetylated mannose triflate, with an activator, tetrabutylammonium bicarbonate. A biol. high quality medicinal environment (sterile and pyrogen-free) was achieved by employment of an inherently pyrodestructive chem. step within the process line and the use of pyrogen-free medical goods and heat-sterilized glassware. [18F]FDG was obtained in 70 min after EOB with a radiochem. yield of 57.7 ¡À 5.7% (decay corrected) and with radiochem. purity of > 99%.
Applied Radiation and Isotopes published new progress about 17351-62-1. 17351-62-1 belongs to catalysis-chemistry, auxiliary class Salt,Amine, name is Tetrabutylammonium hydrogencarbonate, and the molecular formula is C4H6O3, HPLC of Formula: 17351-62-1.
Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia