Zeng, Xiang published the artcileAlterations of the gut microbiota and metabolomics in children with e-waste lead exposure, Safety of 2-Methylbenzoic acid, the publication is Journal of Hazardous Materials (2022), 128842, database is CAplus and MEDLINE.
A lead (Pb) exposure can alter the composition and metabolites of gut microbiota. However, few studies investigated this association in the children. A total of 551 children aged 3-7 years were recruited from Guiyu (the e-waste dismantling area) and Haojiang (the reference area). There were finally 70 subjects met the inclusive criteria. Blood and urinary Pb concentrations were detected by GFAAS and ICP-MS techniques. The microbiota and metabolites were measured in stool samples using 16 S rRNA MiSeq sequencing technol. and gas chromatog.-mass spectrometry (GC-MS), resp. Average Pb concentrations in the blood and urine of children were higher in Guiyu than in Haojiang. There were 58 kinds of differential genera and 19 types of discrepant metabolites between the two groups, and wide and significant correlations were found between them. Exposure to Pb caused the most significant differences in microbiota, metabolites, and phys. development parameters between the two groups in terms of microbiota, metabolites, and phys. development indicators. Sphingolipid metabolism and ion transport may also be altered by Pb exposure. Exposure to Pb is associated with significant alterations in the gut microbiota and metabolome in children. More research is needed to confirm the findings of this study.
Journal of Hazardous Materials published new progress about 118-90-1. 118-90-1 belongs to catalysis-chemistry, auxiliary class Carboxylic acid,Benzene,Natural product, name is 2-Methylbenzoic acid, and the molecular formula is C5H5NO3S, Safety of 2-Methylbenzoic acid.
Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia