Wang, Xiaobin published the artcileSynthesis and antibacterial activity of oxime ester derivatives containing 1,2,4-triazole or 1,3,4-oxadiazole moiety, Formula: C9H7F3O3, the publication is Chemical Papers (2017), 71(10), 1953-1960, database is CAplus.
A series of 1,3,4-oxadiazolyl oxime ester derivatives I [R1 = Me, Et; R2 = 3,4-dimethoxyphenyl, (4-methoxyphenoxy)methyl, [4-(trifluoromethyl)phenoxy]methyl, etc.] and 1,2,4-triazolyl oxime esters II [R1 = Me, Et; R2 = H, F, MeO, etc.] were designed and synthesized and their antibacterial activities in-vitro against Xanthomonas axonopodis pv. citri (Xac) and Xanthomonas oryzae pv. oryzae (Xoo) were evaluated. The bioassays showed that all the title compounds I and II exhibited potent antibacterial activity against Xac and Xoo. In particular, compound I [R1 = Me, R2 = 3,4-dimethoxyphenyl] and compounds II [R1 = Me, R2 = H, F, CF3; R1 = Et, R2 = H, F, CF3] exhibited remarkable antibacterial activity against Xoo, with the EC50 values ranging from 15.15 to 49.34 ¦Ìg/mL, which were superior to that of bismerthiazol (92.61 ¦Ìg/mL). This study indicated that oxime ester derivatives containing 1,2,4-triazole I or 1,3,4-oxadiazole II moiety were used as potential alternative templates in the search for novel antibacterial agents.
Chemical Papers published new progress about 163839-73-4. 163839-73-4 belongs to catalysis-chemistry, auxiliary class Trifluoromethyl,Fluoride,Carboxylic acid,Benzene,Ether, name is 2-(4-(Trifluoromethyl)phenoxy)acetic acid, and the molecular formula is C4H11NO, Formula: C9H7F3O3.
Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia