Sun, Xue-Yi’s team published research in Chinese Chemical Letters in 33 | CAS: 71989-31-6

Chinese Chemical Letters published new progress about 71989-31-6. 71989-31-6 belongs to catalysis-chemistry, auxiliary class Amino acide derivatives,pyrrolidine, name is Fmoc-Pro-OH, and the molecular formula is C3H7NO2, Synthetic Route of 71989-31-6.

Sun, Xue-Yi published the artcileReliable folding of hybrid tetrapeptides into short ¦Â-hairpins, Synthetic Route of 71989-31-6, the publication is Chinese Chemical Letters (2022), 33(1), 257-261, database is CAplus.

Five hybrid tetrapeptides, each consisting a central dipeptide segment of ¦Á-amino acid residues flanked by two aromatic ¦Ã-amino acid residues, are found to fold into well-defined ¦Â-hairpin conformations as shown by NMR, computational study, and X-ray structures. The turn loop of this ¦Â-hairpin motif accommodates different two-residue ¦Á-amino acid sequences from the highly flexible Gly-Gly, to the more restricted D-Pro-Gly. The presence of ¦Á-amino acid side chains enhances the stabilities of the ¦Â-hairpins with the exception of D-Pro-Gly-which results in destabilization. Based on this hairpin/turn motif, a variety of different dipeptide sequences of ¦Á-amino acids which rarely occur in ¦Â-turns can be introduced and presented as two-residue loops.

Chinese Chemical Letters published new progress about 71989-31-6. 71989-31-6 belongs to catalysis-chemistry, auxiliary class Amino acide derivatives,pyrrolidine, name is Fmoc-Pro-OH, and the molecular formula is C3H7NO2, Synthetic Route of 71989-31-6.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia