Wang, Xiaochen published the artcileCombined Photoredox and Carbene Catalysis for the Synthesis of ¦Á-Amino Ketones from Carboxylic Acids, Application In Synthesis of 118-90-1, the publication is ACS Catalysis (2022), 12(4), 2522-2531, database is CAplus.
Herein, a mild, operationally simple method for direct acylation of ¦Á-amino C(sp3)-H bonds from carboxylic acids RC(O)OH (R = cyclopropyl, Ph, 2-chlorophenyl, etc.) via the merger of carbene and photoredox catalysis was reported. Specifically, cross-coupling reactions between a wide range of carboxylic acids, a class of feedstock chems., and readily available N-alkyl anilines R1CH2N(R2)R3 (R1 = H; R2 = Me; R1R2 = -(CH2)3-, -(CH2OCH2CH2)-; R3 = Ph, 4-bromophenyl, pyridin-2-yl, etc.) and 1-phenyl-2,3-dihydro-1H-indole by means of single-electron N-heterocyclic carbene catalysis combined with photocatalysis provided access to structurally diverse ¦Á-amino ketones RC(O)CH(R1)N(R2)R3 and (1-phenylindolin-2-yl)(p-tolyl)methanone. The method features a broad substrate scope and is compatible with a wide array of functional groups. To demonstrate the potential applications of the method, one of the ¦Á-amino ketone products was subjected to further transformations.
ACS Catalysis published new progress about 118-90-1. 118-90-1 belongs to catalysis-chemistry, auxiliary class Carboxylic acid,Benzene,Natural product, name is 2-Methylbenzoic acid, and the molecular formula is C13H10O2, Application In Synthesis of 118-90-1.
Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia