Synthesis and cancer cell cytotoxicity of gold(III) tetraarylporphyrins with a C5-carboxylate substituent was written by Liu, Jinliang;Chen, Huasheng;Li, Yan;Chen, Ying;Mao, Leilei;Xu, Aihua;Wang, Cunde. And the article was included in Journal of Chemical Research in 2011.Name: 4-(10,15,20-Tri-p-tolylporphyrin-5-yl)phenol The following contents are mentioned in the article:
Gold(III) tetraarylporphyrins with a C5-carboxylate substituent were synthesized and their in vitro cytotoxic activity against SGC-<7901¡Ý human gastric cancer cell line panel evaluated. The compound 5-[4-(4-ethoxycarbonylbutoxy)phenyl]-10,15,20-tri(4-methoxyphenyl)porphyrinato gold(III) chloride exhibited significant growth inhibitory properties against SGC-<7901¡Ý human gastric cancer cells and afforded an IC50 value of 29 ¦ÌM for 69.73% of the cell lines in the panel. This study involved multiple reactions and reactants, such as 4-(10,15,20-Tri-p-tolylporphyrin-5-yl)phenol (cas: 57412-08-5Name: 4-(10,15,20-Tri-p-tolylporphyrin-5-yl)phenol).
4-(10,15,20-Tri-p-tolylporphyrin-5-yl)phenol (cas: 57412-08-5) belongs to catalyst ligands. Ligand, in chemistry, any atom or molecule attached to a central atom, usually a metallic element, in a coordination or complex compound. And they often provide a convenient approach to fine-tuning the performance of known catalysts.Name: 4-(10,15,20-Tri-p-tolylporphyrin-5-yl)phenol
Referemce:
Metal catalyst and ligand design,
Ligand Template Strategies for Catalyst Encapsulation – NCBI