Jiang, Chao published the artcileCopper-catalyzed benzylic C-H bond thiocyanation: enabling late-stage diversifications, Recommanded Product: Bis(4-fluorophenyl)methane, the publication is CCS Chemistry (2021), 3(8), 1884-1893, database is CAplus.
The rapid growth of using C-H bond as cross-coupling partners is reshaping the landscape of organic synthesis. C(sp3)-H functionalization via hydrogen atom transfer (HAT) represents the most compelling strategy in this avenue. Here, authors demonstrate an efficient method for benzylic C-H bond thiocyanation via copper-catalyzed radical relay. The reaction exhibits broad substrate scope and exquisite benzylic selectivity with C-H substrates as limiting reagents. In addition, the benzyl thiocyanates are readily converted to other pharmaceutically important motifs, including isothiocyanate, thiourea, and others, highlighting the broad utility of this method.
CCS Chemistry published new progress about 457-68-1. 457-68-1 belongs to catalysis-chemistry, auxiliary class Fluoride,Benzene, name is Bis(4-fluorophenyl)methane, and the molecular formula is C13H10F2, Recommanded Product: Bis(4-fluorophenyl)methane.
Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia