Jiang, Chengjun published the artcileSynergistic Effect of Pd/C and Novozyme 435 on the Dynamic Kinetic Resolution of 1,1,1-trifluoroisopropylamine, Category: catalysis-chemistry, the publication is Chemical Engineering Communications (2016), 203(9), 1222-1226, database is CAplus.
Response surface methodol. (RSM) was successfully applied to study the synergistic effect of Pd/C and Novozyme 435 on the dynamic kinetic resolution of 1,1,1-trifluoroisopropylamine (TFPA). The variables taken into consideration were reaction temperature, substrate concentration, the Pd/C amount, and the Novozyme 435 amount A statistical model was used to evaluate the influence of the variables on the conversion and enantiomeric excess (ee). It was found that the interaction between the Novozyme 435 and Pd/C was a significant parameter that affected TFPA conversion. The optimum conditions for RSM were: reaction temperature of 35¡ãC, substrate (¡À) – 1 concentration of 0.4 mol/L, 60 g/L of Novozyme 435, and 42.4 g/L of Pd/C (3 wt% of Pd on active carbon). The actual exptl. conversion was 95.6% under optimum conditions, which was comparable to the maximum predicted value of 95.7%.
Chemical Engineering Communications published new progress about 421-49-8. 421-49-8 belongs to catalysis-chemistry, auxiliary class Trifluoromethyl,Fluoride,Amine,Aliphatic hydrocarbon chain, name is 1,1,1-Trifluoropropan-2-amine, and the molecular formula is C3H6F3N, Category: catalysis-chemistry.
Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia