Vermeulen, Nicolaas A.’s team published research in Journal of the American Chemical Society in 132 | CAS: 16909-09-4

Journal of the American Chemical Society published new progress about 16909-09-4. 16909-09-4 belongs to catalysis-chemistry, auxiliary class Alkenyl,Carboxylic acid,Benzene,Ether, name is (E)-3-(2,4-Dimethoxyphenyl)acrylic acid, and the molecular formula is C15H21BO2, Product Details of C11H12O4.

Vermeulen, Nicolaas A. published the artcileSynthesis of Complex Allylic Esters via C-H Oxidation vs C-C Bond Formation, Product Details of C11H12O4, the publication is Journal of the American Chemical Society (2010), 132(32), 11323-11328, database is CAplus and MEDLINE.

A highly general, predictably selective C-H oxidation method for the direct, catalytic synthesis of complex allylic esters is introduced. This Pd(II)/sulfoxide-catalyzed method allows a wide range of complex aryl and alkyl carboxylic acids R1CO2H [R1 = Me, Ph, (E)-2,4-(MeO)2C6H3CH:CH, 3,4-F2C6H3CH2, BocNHCH2CH2, etc.] to couple directly with terminal olefins R2CH2CH:CH2 (R2 = Ph, benzodioxolan-5-yl, t-BuSiMe2CH2CH2, etc.) to furnish (E)-allylic esters R2CH:CHCH2OCOR1 in synthetically useful yields and selectivities (16 examples, E/Z ¡Ý 10:1) and without the use of stoichiometric coupling reagents or unstable intermediates. Strategic advantages of constructing allylic esters via C-H oxidation vs C-C bond-forming methods are evaluated and discussed in four “case studies”.

Journal of the American Chemical Society published new progress about 16909-09-4. 16909-09-4 belongs to catalysis-chemistry, auxiliary class Alkenyl,Carboxylic acid,Benzene,Ether, name is (E)-3-(2,4-Dimethoxyphenyl)acrylic acid, and the molecular formula is C15H21BO2, Product Details of C11H12O4.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia